If you use a Nintendo Switch emulator (Ryujinx/Yuzu) or a PS2 emulator (PCSX2):
If you work with large video files or Photoshop renders, using a Ramdisk as a "scratch disk" can drastically speed up rendering times and timeline scrubbing. ramdisk free tool
macOS can create RAM disks via the Terminal using diskutil. Pros: No size limit, very lightweight, portable version