Keep an old MacBook running macOS 10.13 High Sierra or 10.14 Mojave. This is the last OS that can run the 32-bit M-Audio driver. This is impractical for daily production.
Report Date: [Current Date] Product: M-Audio Radium 49 (USB MIDI Controller) Operating System Focus: Apple macOS (v10.5 – v14+)
If you do get the driver working (or if you are using it generically and want to try mapping manually), understanding the Radium's programming is key. Unlike modern controllers that have simple "MIDI Learn" buttons, the Radium 49 requires you to program the messages into the unit itself using the hardware buttons. m-audio radium 49 driver mac
The last Apple operating system that fully supports the Radium 49 driver is macOS Mojave (10.14).
The M-Audio Radium 49 is a legacy USB MIDI controller released in the mid-2000s. Official driver support from M-Audio (inMusic) ceased after macOS 10.14 Mojave. For modern macOS versions (10.15 Catalina through macOS 14 Sonoma and later), the device can only function as a class-compliant MIDI controller without access to advanced features (assignable buttons/faders) unless third-party workarounds are applied. Keep an old MacBook running macOS 10
Why can't you just use it as a generic controller? The Radium 49 was unique because it was essentially two devices in one:
On the back of the Radium 49, there is a standard 5-pin MIDI Out port. This wasn't just for daisy-chaining; it allowed you to use the Radium as an interface for other hardware. You could plug a hardware synth into the Radium, and the Radium into the Mac, and sequence the synth. On the back of the Radium 49, there
Without the specific driver, this pass-through functionality is almost always lost. If you rely on the Radium to control external sound modules, you may find that the data isn't being transmitted correctly from the Mac to the external gear.